Glucocorticoid Receptor - summary

7241868	Crystallization of Glucocorticoid Receptor Provided are crystals relating to human Glucocorticoid Receptor and its various uses.
7238778	Crystallized glucocorticoid receptor ligand binding domain polypeptide and screening methods employing same A method of modifying a test nuclear receptor (NR) polypeptide is disclosed. The method provides a test NR polypeptide sequence having a characteristic that is targeted for modification; aligning...
US20070020684	Structure of a glucocorticoid receptor ligand binding domain comprising an expanded binding pocket and methods employing same A solved three-dimensional crystal structure of a glucocorticord receptor (GR) α ligand binding domain polypeptide is disclosed, in the form of a crystalline glucocorticord receptor α ligand...
US20050181362	Crystallized glucocorticoid receptor ligand binding domain polypeptide and screening methods employing same A method of modifying a test nuclear receptor (NR) polypeptide is disclosed. The method provides a test NR polypeptide sequence having a characteristic that is targeted for modification; aligning...
WO/2003/090666A2	GLUCOCORTICOID RECEPTOR PROTEIN CRYSTALS The present invention is in the fields of biotechnology, protein purification and crystallization, x-ray diffraction analysis, three-dimensional computer molecular modeling and rational drug...
WO/2003/015692A2	CRYSTALLIZED GLUCOCORTICOID RECEPTOR LIGAND BINDING DOMAIN POLYPEPTIDE AND SCREENING METHODS EMPLOYING SAME A method of modifying a test nuclear receptor (NR) polypeptide is disclosed. The method provides a test NR polypeptide sequence having a characteristic that is targeted for modification; aligning...

VEGFR - summary

US20050197492	Crystal structure of VEGFRKD: ligand complexes and methods of use thereof Polypeptides containing the kinase domain of a VEGFR are described. Also described are crystal structures of these polypeptides, including the crystal structures of VEGFR2KD:ligand complexes. The...
6849721	Modifications of the VEGF receptor-2 protein and methods of use A 2.4 Å crystal structure of a protein construct containing the catalytic kinase domain of vascular endothelial growth factor receptor 2 (VEGFR2/KDR), a key enzyme in angiogenesis, has been...
WO/2004/092217A1	CRYSTAL STRUCTURE OF VEGFRKD: LIGAND COMPLEXES AND METHODS OF USE THEREOF Polypeptides containing the kinase domain of a VEGFR are described. Also described are crystal structures of these polypeptides, including the crystal structures of VEGFR2KD: ligand complexes. The...
6794146	Modifications of the VEGF receptor-2 protein and methods of use A 2.4 Å crystal structure of a protein construct containing the catalytic kinase domain of vascular endothelial growth factor receptor 2 (VEGFR2/KDR), a key enzyme in angiogenesis, has been...
6784285	Modifications of the VEGF Receptor-2 Protein and methods of use A 2.4 Å crystal structure of a protein construct containing the catalytic kinase domain of vascular endothelial growth factor receptor 2 (VEGFR2/KDR), a key enzyme in angiogenesis, has been...
6753416	Modifications of the VEGF receptor-2 protein and methods of use A 2.4 Å crystal structure of a protein construct containing the catalytic kinase domain of vascular endothelial growth factor receptor 2 (VEGFR2/KDR), a key enzyme in angiogenesis, has been...
US20020164641	Modifications of the VEGF receptor-2 protein and methods of use A 2.4 Å crystal structure of a protein construct containing the catalytic kinase domain of vascular endothelial growth factor receptor 2 (VEGFR2/KDR), a key enzyme in angiogenesis, has been...
US20020127538	Modifications of the VEGF receptor-2 protein and methods of use A 2.4 Å crystal structure of a protein construct containing the catalytic kinase domain of vascular endothelial growth factor receptor 2 (VEGFR2/KDR), a key enzyme in angiogenesis, has been...
US20020051965	Modifications of the VEGF receptor-2 protein and methods of use A 2.4 Å crystal structure of a protein construct containing the catalytic kinase domain of vascular endothelial growth factor receptor 2 (VEGFR2/KDR), a key enzyme in angiogenesis, has been...
6316603	Modifications of the VEGF receptor-2 protein and methods of use A 2.4 Å crystal structure of a protein construct containing the catalytic kinase domain of vascular endothelial growth factor receptor 2 (VEGFR2/KDR), a key enzyme in angiogenesis, has been...
WO/2000/014105A1	MODIFICATIONS OF THE VEGF RECEPTOR-2 PROTEIN AND METHODS OF USE A 2.4 Å crystal structure of a protein construct containing the catalytic kinase domain of vascular endothelial growth factor receptor 2 (VEGFR2/KDR), a key enzyme in angiogenesis, has been...