Saturday, July 19, 2008

Ribosome structures - summary

US20060136146

MODULATORS OF RIBOSOMAL FUNCTION AND IDENTIFICATION THEREOF
The invention provides methods for producing high resolution crystals of ribosomes and ribosomal subunits as well as crystals produced by such methods. The invention also provides high resolution...

US20050272681

Ribosome structure and protein synthesis inhibitors
The invention provides methods for producing high resolution crystals of ribosomes and ribosomal subunits as well as crystals produced by such methods. The invention also provides high resolution...

US20050234227

Ribosome structure and protein synthesis inhibitors
The invention provides methods for producing high resolution crystals of ribosomes and ribosomal subunits as well as crystals produced by such methods. The invention also provides high resolution...

US20050233349

Crystal structure of ribosomal protein L11/GTPase activating region rRNA and uses thereof
The present invention is broadly directed to methods of screening ribosomal protein L 11 /GTPase activating region (GAR) RNA-modulating compounds by using information from the high-resolution...

US20050154538

Crystal structure of the 30S ribosome and its use
The invention provides an X-ray crystal structure of the 30S ribosome, obtained from Thermus thermophilus 30S subunit, having a tetragonal space group P4 1 2 1 2 with unit cell dimensions of...

US20050036997

RIBOSOME STRUCTURE AND PROTEIN SYNTHESIS INHIBITORS
The invention provides methods for producing high resolution crystals of ribosomes and ribosomal subunits as well as crystals produced by such methods. The invention also provides high resolution...

US20040265984

Methods of growing crystals of free, antibiotic-complexed, and substrate-complexed large ribosomal subunits, and methods of rationally designing or identifying antibiotics using structure coordinate data derived from such crystals
Methods of growing crystals of free, antibiotic complexed, or ribosomal substrate complexed large ribosomal subunits, coordinates defining the three-dimensional atomic structure thereof and methods...

US20040034207

Crystal structure of antibiotics bound to the 30S ribosome and its use
The invention provides high resolution X-ray crystal structures of the 30S ribosome, obtained from Thermus thermophilus 30S subunit, having a tetragonal space group P4 1 2 1 2 to which are bound...

US20030232779

Determination and uses of the atomic structures of ribosomes and ribosomal subunits and their ligand complexes
The present invention provides methods for producing high resolution crystals of ribosomes and ribosomal subunits as well as the crystals produced by such methods. The x-ray diffraction patterns of...

US20030171327

Determination and uses of the atomic structures of ribosomes and ribosomal subunits and their ligand complexes
The present invention provides methods for producing high resolution crystals of ribosomes and ribosomal subunits as well as the crystals produced by such methods. The x-ray diffraction patterns of...

US20030153002

Ribosome structure and protein synthesis inhibitors
The invention provides methods for producing high resolution crystals of ribosomes and ribosomal subunits as well as crystals produced by such methods. The invention also provides high resolution...

US20030099955

Crystal structure of ribosomal protein L11/GTPase activating region rRNA and uses thereof
The present invention is broadly directed to methods of screening ribosomal protein L11/GTPase activating region (GAR) RNA-modulating compounds by using information from the high-resolution...

US20030027315

Methods of growing crystals of free and antibiotic complexed large ribosomal subunits, and methods of rationally designing or identifying antibiotics using structure coordinate data derived from such crystals
Methods of growing crystals of free and antibiotic complexed large ribosomal subunits, coordinates defining the 3D atomic structure thereof and methods of utilizing such coordinates for rational...

US20020188108

X-ray crystal structures of functional ribosome complexes containing transfer RNA and model messenger RNAs and methods of use
Structures of 70S ribosome complexes containing messenger RNA and transfer RNA (tRNA), or tRNA analogs, have been solved by x-ray crystallography at up to 5.5 Angstrom resolution. Many details of...

US20020106660

Crystal structure of the 30s ribosome and its use
The invention provides an X-ray crystal structure of the 30S ribosome, obtained from Thermus thermophilus 30S subunit, having a tetragonal space group P4 1 2 1 2 with unit cell dimensions of...

US20020086308

Ribosome structure and protein synthesis inhibitors
The invention provides methods for producing high resolution crystals of ribosomes and ribosomal subunits as well as crystals produced by such methods. The invention also provides high resolution...

US20020072861

Crystal structure of antibiotics bound to the 30S ribosome and its use
The invention provides high resolution X-ray crystal structures of the 30S ribosome, obtained from Thermus thermophilus 30S subunit, having a tetragonal space group P4 1 2 1 2 to which are bound...